Novel approach to continuous adventitious respiratory sound analysis for the assessment of bronchodilator response.

ABSTRACT:

Background

A thorough analysis of continuous adventitious sounds (CAS) can provide distinct and complementary information about bronchodilator response (BDR), beyond that provided by spirometry. Nevertheless, previous approaches to CAS analysis were limited by certain methodology issues. The aim of this study is to propose a new integrated approach to CAS analysis that contributes to improving the assessment of BDR in clinical practice for asthma patients.

Methods

Respiratory sounds and flow were recorded in 25 subjects, including 7 asthma patients with positive BDR (BDR+), assessed by spirometry, 13 asthma patients with negative BDR (BDR-), and 5 controls. A total of 5149 acoustic components were characterized using the Hilbert spectrum, and used to train and validate a sup

SUBMITTER: Lozano-Garcia M 

PROVIDER: S-EPMC5298277 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature