Metabolic Phenotype and Risk of Colorectal Cancer in Normal-Weight Postmenopausal Women.

ABSTRACT:

Background

The prevalence of metabolically unhealthy phenotype in normal-weight adults is 30%, and few studies have explored the association between metabolic phenotype and colorectal cancer incidence in normal-weight individuals. Our aim was to compare the risk of colorectal cancer in normal-weight postmenopausal women who were characterized by either the metabolically healthy phenotype or the metabolically unhealthy phenotype.

Methods

A large prospective cohort, the Women's Health Initiative, was used. The analytic sample included 5,068 postmenopausal women with BMI 18.5 to <25 kg/m² Metabolic phenotype was defined using the Adult Treatment Panel-III definition, excluding waist circumference; therefore, women with one or none of the four components (elevated tri

SUBMITTER: Liang X 

PROVIDER: S-EPMC5301805 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature