Sex-Based Differences in Cardiometabolic Biomarkers.

ABSTRACT:

Background

Few data are available comparing cardiovascular disease (CVD) biomarker profiles between women and men in the general population. We analyzed sex-based differences in multiple biomarkers reflecting distinct pathophysiological pathways, accounting for differences between women and men in CVD risk factors, body composition, and cardiac morphology.

Methods

A cross-sectional analysis was performed using data from the Dallas Heart Study, a multiethnic population-based study. Associations between sex and 30 distinct biomarkers representative of 6 pathophysiological categories were evaluated using multivariable linear regression adjusting for age, race, traditional CVD risk factors, kidney function, insulin resistance, MRI and dual-energy x-ray absorptiometry measures of

SUBMITTER: Lew J 

PROVIDER: S-EPMC5302552 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature