Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial.

ABSTRACT:

Background

There is increasing interest in the role of physical exercise as a therapeutic strategy for individuals with Alzheimer's disease (AD). We assessed the effect of 26 weeks (6 months) of a supervised aerobic exercise program on memory, executive function, functional ability and depression in early AD.

Methods and findings

This study was a 26-week randomized controlled trial comparing the effects of 150 minutes per week of aerobic exercise vs. non-aerobic stretching and toning control intervention in individuals with early AD. A total of 76 well-characterized older adults with probable AD (mean age 72.9 [7.7]) were enrolled and 68 participants completed the study. Exercise was conducted with supervision and monitoring by trained exercise specialists. Neuropsychologica

SUBMITTER: Morris JK 

PROVIDER: S-EPMC5302785 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature