What's the remedy for the distal necrosis of DIEP flap, better venous drain or more arterial supply?

ABSTRACT:

Background

We developed a novel pedicled DIEP flap model in rat to explore the possible remedy for the distal necrosis of the flap.

Methods

A deep inferior epigastric perforator (DIEP) flap, based on the second right cranial perforator (P2) as the main pedicle, was elevated in 48 Sprague-Dawley rats. The rats were randomized into 4 groups: group I, the left P2 remaining intact as supercharging; group II, the left P2 artery alone kept as supercharging; group III, the left P2 vein alone kept as supercharging; group IV, no supercharging. Transcutaneous oxygen pressure (TcPO2) and transcutaneous carbon dioxide pressure (TcPCO2) were measured immediately after flap elevation, protein level of Hif-1a was measured 48 hours later, and flap survival was assessed 7 days postoperativel

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5302794 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature