Stimulation of the Posterior Cortical-Hippocampal Network Enhances Precision of Memory Recollection.

ABSTRACT: Episodic memory is thought to critically depend on interaction of the hippocampus with distributed brain regions [1-3]. Specific contributions of distinct networks have been hypothesized, with the hippocampal posterior-medial (HPM) network implicated in the recollection of highly precise contextual and spatial information [3-6]. Current evidence for HPM specialization is mostly indirect, derived from correlative measures such as neural activity recordings. Here we tested the causal role of the HPM network in recollection using network-targeted noninvasive brain stimulation in humans, which has previously been shown to increase functional connectivity within the HPM network [7]. Effects of multiple-day electromagnetic stimulation were assessed using an object-location memory task that segre

SUBMITTER: Nilakantan AS 

PROVIDER: S-EPMC5302852 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature