Measles and Rubella Seroprevalence Among HIV-infected and Uninfected Zambian Youth.

ABSTRACT:

Background

Measles and congenital rubella syndrome remain significant causes of morbidity and mortality despite available vaccines. HIV-infected youth may be at increased risk of measles because of greater waning immunity after vaccination. At a population level, they constitute a potentially large pool of susceptibles to measles and rubella. More data among HIV-infected youth in sub-Saharan Africa are needed to guide vaccination policy and control strategies.

Methods

This cross-sectional study was nested within 2 ongoing studies of malaria and HIV in Zambia. Dried blood spot cards from youth (5-15 years) in these studies from 2009 to 2013 were tested for IgG antibodies to measles and rubella viruses. HIV-uninfected youth, HIV-infected treatment-naive youth and HIV-infected

SUBMITTER: Sutcliffe CG 

PROVIDER: S-EPMC5303148 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature