Resting state connectivity of the human habenula at ultra-high field.

ABSTRACT: The habenula, a portion of the epithalamus, is implicated in the pathophysiology of depression, anxiety and addiction disorders. Its small size and connection to other small regions prevent standard human imaging from delineating its structure and connectivity with confidence. Resting state functional connectivity is an established method for mapping connections across the brain from a seed region of interest. The present study takes advantage of 7T fMRI to map, for the first time, the habenula resting state network with very high spatial resolution in 32 healthy human participants. Results show novel functional connections in humans, including functional connectivity with the septum and bed nucleus of the stria terminalis (BNST). Results also show many habenula connections previously desc

SUBMITTER: Torrisi S 

PROVIDER: S-EPMC5303669 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature