Chronnectomic patterns and neural flexibility underlie executive function.

ABSTRACT: Despite extensive research into executive function (EF), the precise relationship between brain dynamics and flexible cognition remains unknown. Using a large, publicly available dataset (189 participants), we find that functional connections measured throughout 56min of resting state fMRI data comprise five distinct connectivity states. Elevated EF performance as measured outside of the scanner was associated with greater episodes of more frequently occurring connectivity states, and fewer episodes of less frequently occurring connectivity states. Frequently occurring states displayed metastable properties, where cognitive flexibility may be facilitated by attenuated correlations and greater functional connection variability. Less frequently occurring states displayed properties consisten

SUBMITTER: Nomi JS 

PROVIDER: S-EPMC5303676 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature