Ontology highlight
ABSTRACT:
SUBMITTER: Law PJ
PROVIDER: S-EPMC5303820 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Nature communications 20170206
Several chronic lymphocytic leukaemia (CLL) susceptibility loci have been reported; however, much of the heritable risk remains unidentified. Here we perform a meta-analysis of six genome-wide association studies, imputed using a merged reference panel of 1,000 Genomes and UK10K data, totalling 6,200 cases and 17,598 controls after replication. We identify nine risk loci at 1p36.11 (rs34676223, P=5.04 × 10<sup>-13</sup>), 1q42.13 (rs41271473, P=1.06 × 10<sup>-10</sup>), 4q24 (rs71597109, P=1.37 ...[more]