Maternal Prepregnancy BMI and Glucose Level at 24-28 Gestational Weeks on Offspring's Overweight Status within 3 Years of Age.

ABSTRACT: Objective. To examine the relative impact of maternal prepregnancy body mass index (BMI) and glucose level at 24-28 gestational weeks on offspring's overweight status from birth to 3 years of age in China. Methods. Health care records of 21,354 mother-child pairs were collected. The single and joint associations of maternal prepregnancy BMI and glucose level at 24-28 gestational weeks with 0-3-year-old offspring's overweight status were assessed. Results. The odds ratios (95% confidence intervals) of offspring's macrosomia at birth and overweight/obesity at the 12th month, 24th month, and 36th month were 1.12 (1.11-1.13), 1.05 (1.04-1.06), 1.07 (1.06-1.08), and 1.11 (1.10-1.12) for each 1-unit increase (km/m²) in maternal prepregnancy BMI and 1.13 (1.10-1.17

SUBMITTER: Li W 

PROVIDER: S-EPMC5303844 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature