Pitfalls of invasive blood pressure monitoring using the caudal ventral artery in rats.

ABSTRACT: During rodent experiments, the caudal ventral artery (CVA) is useful for blood pressure (BP) measurement. However, CVA measurements may not reflect the true BP. This study was performed to verify the site-specific accuracy of invasive arterial BP monitoring during surgery in rats. Invasive arterial BP was simultaneously measured in rats via the CVA and the common carotid artery (CCA). The BP values were analysed while the rats were subjected to cooling of the head or tail. Additionally, the rats underwent digital subtraction angiography and histological examination of these arteries. The pressure difference was more significant in the tail cooling group than in the head cooling group. Digital subtraction angiography revealed that angiospasms occurred more frequently in the CVA than in the

SUBMITTER: Ohta H 

PROVIDER: S-EPMC5304151 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature