Plasmid Replicons from Pseudomonas Are Natural Chimeras of Functional, Exchangeable Modules.

ABSTRACT: Plasmids are a main factor for the evolution of bacteria through horizontal gene exchange, including the dissemination of pathogenicity genes, resistance to antibiotics and degradation of pollutants. Their capacity to duplicate is dependent on their replication determinants (replicon), which also define their bacterial host range and the inability to coexist with related replicons. We characterize a second replicon from the virulence plasmid pPsv48C, from Pseudomonas syringae pv. savastanoi, which appears to be a natural chimera between the gene encoding a newly described replication protein and a putative replication control region present in the widespread family of PFP virulence plasmids. We present extensive evidence of this type of chimerism in structurally similar replicons fr

SUBMITTER: Bardaji L 

PROVIDER: S-EPMC5304414 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature