Increased risk of dementia in patients hospitalized with acute kidney injury: A nationwide population-based cohort study.

ABSTRACT:

Purpose

To determine whether acute kidney injury (AKI) is a risk factor for dementia.

Methods

This nationwide population-based cohort study was based on data from the Taiwan National Health Insurance Research Database for 2000-2011. The incidence and relative risk of dementia were assessed in 207788 patients hospitalized for AKI. The comparison control was selected using the propensity score based on age, sex, index year and comorbidities.

Results

During the 12-year follow-up, patients with AKI had a significantly higher incidence for developing dementia than did the controls (8.84 vs 5.75 per 1000 person-y). A 1.88-fold increased risk of dementia (95% confidence interval, 1.76-2.01) was observed after adjustment for age, sex, and several comorbidities (diabetes, hype

SUBMITTER: Tsai HH 

PROVIDER: S-EPMC5305096 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature