Vitamin D deficiency is significantly associated with depression in patients with chronic kidney disease.

ABSTRACT:

Background

Depression is reported to be the most common psychological problem in patients with chronic kidney disease (CKD). Several studies have reported that lower levels of serum vitamin D are significantly associated with depression. Both vitamin D deficiency and depression are prevalent in patients with CKD, yet the relationship between these two factors remains poorly understood. This study aimed to investigate the association between vitamin D levels and depression among CKD patients.

Methods

Totally, 21,257 individuals who participated in the Korean National Health and Nutrition Examination Survey (KNHANES V, VI) from 2010-2014 were screened for the study; 533 CKD patients were included. Vitamin D deficiency was defined as serum 25-hydroxyvitamin D3 [25(OH)D3] ≤10 ng

SUBMITTER: Jhee JH 

PROVIDER: S-EPMC5305247 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature