In vivo response to polypropylene following implantation in animal models: a review of biocompatibility.

ABSTRACT:

Introduction and hypothesis

Polypropylene is a material that is commonly used to treat pelvic floor conditions such as pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Owing to the nature of complications experienced by some patients implanted with either incontinence or prolapse meshes, the biocompatibility of polypropylene has recently been questioned. This literature review considers the in vivo response to polypropylene following implantation in animal models. The specific areas explored in this review are material selection, impact of anatomical location, and the structure, weight and size of polypropylene mesh types.

Methods

All relevant abstracts from original articles investigating the host response of mesh in vivo were reviewed. Papers were obtaine

SUBMITTER: Kelly M 

PROVIDER: S-EPMC5306078 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature