Lack of Evidence to Guide Deprescribing of Antihyperglycemics: A Systematic Review.

ABSTRACT:

Introduction

Individualizing glycemic targets to goals of care and time to benefit in persons with type 2 diabetes is good practice, particularly in populations at risk of hypoglycemia and adverse outcomes relating to the use of antihyperglycemics. Guidelines acknowledge the need for relaxed targets in frail older adults, but there is little guidance on how to safely deprescribe (i.e. stop, reduce or substitute) antihyperglycemics.

Methods

The purpose of this study was to synthesize evidence from all studies evaluating the effects of deprescribing versus continuing antihyperglycemics in older adults with type 2 diabetes. To this end, we searched MEDLINE, EMBASE, and Cochrane Library (July 2015) for controlled studies evaluating the effects of deprescribing antihyperglycemics

SUBMITTER: Black CD 

PROVIDER: S-EPMC5306119 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature