Reliable nanomaterial classification of powders using the volume-specific surface area method.

ABSTRACT: The volume-specific surface area (VSSA) of a particulate material is one of two apparently very different metrics recommended by the European Commission for a definition of "nanomaterial" for regulatory purposes: specifically, the VSSA metric may classify nanomaterials and non-nanomaterials differently than the median size in number metrics, depending on the chemical composition, size, polydispersity, shape, porosity, and aggregation of the particles in the powder. Here we evaluate the extent of agreement between classification by electron microscopy (EM) and classification by VSSA on a large set of diverse particulate substances that represent all the anticipated challenges except mixtures of different substances. EM and VSSA are determined in multiple labs to assess also the level of rep

SUBMITTER: Wohlleben W 

PROVIDER: S-EPMC5306339 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature