Associations between IVF outcomes and essential trace elements measured in follicular fluid and urine: a pilot study.

ABSTRACT:

Purpose

A hypothesis-generating pilot study exploring associations between essential trace elements measured in follicular fluid (FF) and urine and in vitro fertilization (IVF) endpoints.

Methods

We recruited 58 women undergoing IVF between 2007 and 2008, and measured cobalt, chromium, copper, manganese, molybdenum, and zinc in FF (n = 46) and urine (n = 45) by inductively coupled plasma mass spectrometry (ICP-MS). We used multivariable regression models to assess the impact of FF and urine trace elements on IVF outcomes, adjusted for age, body mass index, race, and cigarette smoking.

Results

Trace elements were mostly present at lower concentrations in FF than in urine. The average number of oocytes retrieved was positively associated with higher urine cobalt, chromi

SUBMITTER: Ingle ME 

PROVIDER: S-EPMC5306414 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature