International clinical guideline for the management of classical galactosemia: diagnosis, treatment, and follow-up.

ABSTRACT: Classical galactosemia (CG) is an inborn error of galactose metabolism. Evidence-based guidelines for the treatment and follow-up of CG are currently lacking, and treatment and follow-up have been demonstrated to vary worldwide. To provide patients around the world the same state-of-the-art in care, members of The Galactosemia Network (GalNet) developed an evidence-based and internationally applicable guideline for the diagnosis, treatment, and follow-up of CG. The guideline was developed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. A systematic review of the literature was performed, after key questions were formulated during an initial GalNet meeting. The first author and one of the working group experts conducted data-extraction. All exper

SUBMITTER: Welling L 

PROVIDER: S-EPMC5306419 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature