Patterns of antiplatelet drug use after a first myocardial infarction during a 10-year period.

ABSTRACT:

Aims

The aims of the present study were to assess antiplatelet drug use patterns after a first myocardial infarction (MI) and to evaluate the determinants of antiplatelet nonpersistence.

Methods

The present study was conducted in 4690 patients from the Utrecht Cardiovascular Pharmacogenetics cohort with a first MI between 1986 and 2010, who were followed for a maximum of 10 years. Medication use and event diagnosis were obtained from the Dutch PHARMO Record Linkage System. Antiplatelet drug users were classified as persistent users (gap between prescriptions ≤90 days), nonpersistent users (>90-day gap and no refills), and restarters (a new prescription after a >90-day gap). The association between potential determinants and antiplatelet nonpersistence was analysed using Cox

SUBMITTER: Yasmina A 

PROVIDER: S-EPMC5306486 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature