Effects of policy interventions on the introduction of novel oral anticoagulants in Stockholm: an interrupted time series analysis.

ABSTRACT:

Aims

The aim of the present study was to assess the effect of policy interventions - i.e. reimbursement decisions, guidelines and regional recommendations - on the prescribing of oral anticoagulant treatment in patients with atrial fibrillation (AF).

Methods

Interrupted time series analyses were carried out using monthly data on all patients with a recorded diagnosis of AF newly initiated (switchers and anticoagulant-naïve patients alike) on warfarin, dabigatran, rivaroxaban or apixaban in the Stockholm region from April 2011 until February 2016.

Results

A total of 34 165 initiations in 27 942 patients were included. The publication of the European Guidelines was associated with an increase in novel oral anticoagulant (NOAC) initiations of 12.5% [95% confidence interv

SUBMITTER: Komen J 

PROVIDER: S-EPMC5306490 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature