Eda haplotypes in three-spined stickleback are associated with variation in immune gene expression.

ABSTRACT: Haplotypes underlying local adaptation and speciation are predicted to have numerous phenotypic effects, but few genes involved have been identified, with much work to date concentrating on visible, morphological, phenotypes. The link between genes controlling these adaptive morphological phenotypes and the immune system has seldom been investigated, even though changes in the immune system could have profound adaptive consequences. The Eda gene in three-spined stickleback is one of the best studied major adaptation genes; it directly controls bony plate architecture and has been associated with additional aspects of adaptation to freshwater. Here, we exposed F2 hybrids, used to separate Eda genotype from genetic background, to contrasting conditions in semi-natural enclosures. We demonstr

SUBMITTER: Robertson S 

PROVIDER: S-EPMC5307360 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature