Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

ABSTRACT: Botulinum neurotoxins are diverse proteins. They are currently represented by at least seven serotypes and more than 40 subtypes. New clostridial strains that produce novel neurotoxin variants are being identified with increasing frequency, which presents challenges when organizing the nomenclature surrounding these neurotoxins. Worldwide, researchers are faced with the possibility that toxins having identical sequences may be given different designations or novel toxins having unique sequences may be given the same designations on publication. In order to minimize these problems, an ad hoc committee consisting of over 20 researchers in the field of botulinum neurotoxin research was convened to discuss the clarification of the issues involved in botulinum neurotoxin nomenclature. This publ

SUBMITTER: Peck MW 

PROVIDER: S-EPMC5308270 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature