Derivation of a Predictive Model for Graft Loss Following Acute Kidney Injury in Kidney Transplant Recipients.

ABSTRACT:

Background

Acute kidney injury (AKI) is common in the kidney transplant population.

Objective

To derive a multivariable survival model that predicts time to graft loss following AKI.

Design

Retrospective cohort study using health care administrative and laboratory databases.

Setting

Southwestern Ontario (1999-2013) and Ottawa, Ontario, Canada (1996-2013).

Patients

We included first-time kidney only transplant recipients who had a hospitalization with AKI 6 months or greater following transplant.

Measurements

AKI was defined using the Acute Kidney Injury Network criteria (stage 1 or greater). The first episode of AKI was included in the analysis. Graft loss was defined by return to dialysis or repeat kidney transplant.

Methods

We performed a

SUBMITTER: Molnar AO 

PROVIDER: S-EPMC5308519 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature