Microstructure of the Default Mode Network in Preterm Infants.

ABSTRACT:

Background and purpose

Diffusion and fMRI has been providing insights to brain development in addition to anatomic imaging. This study aimed to evaluate the microstructure of white matter tracts underlying the default mode network in premature infants by using resting-state functional MR imaging in conjunction with diffusion tensor imaging-based tractography.

Materials and methods

A cohort of 44 preterm infants underwent structural T1-weighted imaging, resting-state fMRI, and DTI at 3T, including 21 infants with brain injuries and 23 infants with normal-appearing structural imaging as controls. Neurodevelopment was evaluated with the Bayley Scales of Infant Development at 12 months' adjusted age. Probabilistic independent component analysis was applied to resting-state fMRI

SUBMITTER: Cui J 

PROVIDER: S-EPMC5309151 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature