Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids.

ABSTRACT:

Background

Corynebacterium glutamicum is a non-pathogenic bacterium widely used in industrial amino acid production and metabolic engineering research. Although the genome sequences of some C. glutamicum strains are available, comprehensive comparative genome analyses of these species have not been done. Six wild type C. glutamicum strains were sequenced using next-generation sequencing technology in our study. Together with 20 previously reported strains, we present a comprehensive comparative analysis of C. glutamicum genomes.

Results

By average nucleotide identity (ANI) analysis, we show that 10 strains, which were previously classified either in the genus Brevibacterium, or as some other species within the genus Corynebacterium, should be reclassified as members of the s

SUBMITTER: Yang J 

PROVIDER: S-EPMC5310272 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature