Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.

ABSTRACT:

Background

Targeted temperature management is recommended for comatose adults and children after out-of-hospital cardiac arrest; however, data on temperature management after in-hospital cardiac arrest are limited.

Methods

In a trial conducted at 37 children's hospitals, we compared two temperature interventions in children who had had in-hospital cardiac arrest. Within 6 hours after the return of circulation, comatose children older than 48 hours and younger than 18 years of age were randomly assigned to therapeutic hypothermia (target temperature, 33.0°C) or therapeutic normothermia (target temperature, 36.8°C). The primary efficacy outcome, survival at 12 months after cardiac arrest with a score of 70 or higher on the Vineland Adaptive Behavior Scales, second edition (VAB

SUBMITTER: Moler FW 

PROVIDER: S-EPMC5310766 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature