Evaluation of liver cirrhosis and hepatocellular carcinoma using Protein-Protein Interaction Networks.

ABSTRACT:

Aim

In the current study, we analysised only the articles that investigate serum proteome profile of cirrhosis patients or HCC patients versus healthy controls.

Background

Increased understanding of cancer biology has enabled identification of molecular events that lead to the discovery of numerous potential biomarkers in diseases. Protein-protein interaction networks is one of aspect that could elevate the understanding level of molecular events and protein connections that lead to the identification of genes and proteins associated with diseases.

Methods

Gene expression data, including 63 gene or protein names for hepatocellular carcinoma and 29 gene or protein names for cirrhosis, were extracted from a number of previous investigations. The networks of related diff

SUBMITTER: Ehsani Ardakani MJ 

PROVIDER: S-EPMC5310795 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature