Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data.

ABSTRACT: Objectives To assess the overall effect of vitamin D supplementation on risk of acute respiratory tract infection, and to identify factors modifying this effect.Design Systematic review and meta-analysis of individual participant data (IPD) from randomised controlled trials.Data sources Medline, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, ClinicalTrials.gov, and the International Standard Randomised Controlled Trials Number registry from inception to December 2015.Eligibility criteria for study selection Randomised, double blind, placebo controlled trials of supplementation with vitamin D₃ or vitamin D₂ of any duration were eligible for inclusion if they had been approved by a research ethics committee and if

SUBMITTER: Martineau AR 

PROVIDER: S-EPMC5310969 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature