Management of Multiple Nitrogen Sources during Wine Fermentation by Saccharomyces cerevisiae.

ABSTRACT: During fermentative growth in natural and industrial environments, Saccharomyces cerevisiae must redistribute the available nitrogen from multiple exogenous sources to amino acids in order to suitably fulfill anabolic requirements. To exhaustively explore the management of this complex resource, we developed an advanced strategy based on the reconciliation of data from a set of stable isotope tracer experiments with labeled nitrogen sources. Thus, quantifying the partitioning of the N compounds through the metabolism network during fermentation, we demonstrated that, contrary to the generally accepted view, only a limited fraction of most of the consumed amino acids is directly incorporated into proteins. Moreover, substantial catabolism of these molecules allows for efficient redistributi

SUBMITTER: Crepin L 

PROVIDER: S-EPMC5311416 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature