Ontology highlight
ABSTRACT:
SUBMITTER: Gerland TA
PROVIDER: S-EPMC5312933 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
PloS one 20170216 2
Hybrid incompatibility between Drosophila melanogaster and D. simulans is caused by a lethal interaction of the proteins encoded by the Hmr and Lhr genes. In D. melanogaster the loss of HMR results in mitotic defects, an increase in transcription of transposable elements and a deregulation of heterochromatic genes. To better understand the molecular mechanisms that mediate HMR's function, we measured genome-wide localization of HMR in D. melanogaster tissue culture cells by chromatin immunopreci ...[more]