Antecedent longitudinal changes in body mass index are associated with diurnal cortisol curve features: The multi-ethnic study of atherosclerosis.

ABSTRACT:

Context

Prior studies have shown a cross-sectional association between body mass index (BMI) and salivary diurnal cortisol profile features (cortisol features); however, to our knowledge prior population-based studies have not examined the longitudinal association of body-mass index (BMI) with cortisol features.

Objective

To examine the association of (1) prior annual BMI percent change over 7years with cortisol features, (2) baseline cortisol features with subsequent change in BMI over 6years and (3) the association of change in cortisol features with change in BMI over 6years.

Design

Longitudinal study.

Setting

Multi-Ethnic Study of Atherosclerosis (MESA) Stress I & II Studies (2004-2006 & 2010-2012).

Participants

1685 ethnically diverse men and women

SUBMITTER: Joseph JJ 

PROVIDER: S-EPMC5312946 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature