A higher baseline plasma uric acid level is an independent predictor of arterial stiffness: A community-based prospective study.

ABSTRACT: Hyperuricemia has been demonstrated to be a risk factor for cardiovascular diseases. Though the association between uric acid (UA) and arterial stiffness has been investigated previously in patients with basic diseases, the predictive value of baseline UA level for arterial stiffness has not been conducted. We aimed at identifying the predictive role of UA for arterial stiffness prospectively.A longitudinal follow-up study in a routine health check-up population was performed with an average follow-up of 4.8 years. The demographic information, baseline and follow-up anthropometric parameters, arterial stiffness (pulse-wave velocity, PWV), and biomarker variables including UA have been measured and analyzed.A total of 1447 valid follow-ups were available for the final analysis. Both of the

SUBMITTER: Ding XH 

PROVIDER: S-EPMC5312993 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature