Plasma fibrin D-dimer and the risk of left atrial thrombus: A systematic review and meta-analysis.

ABSTRACT:

Background

Plasma fibrin d-dimer has been taken as a marker for thrombus. The aim of this study was to evaluate the relationship between d-dimer (DD) levels and left atrial spontaneous echo contrast (SEC)/left atrial thrombus (LAT).

Methods

We identified clinical studies by systematic search of MEDLINE and EMBASE databases up to Feb 2016. All observational studies that considered DD as a study factor and trans-esophageal echocardiography (TEE) identified SEC/LAT as an outcome were included. Two reviewers independently selected the studies and extracted the data.

Results

Of the 21 included studies, 16 studies (2652 patients) have compared the mean DD differences between patients with and without an evidence of the presence of SEC/LAT, 9 studies (1667 patients) have est

SUBMITTER: Wan H 

PROVIDER: S-EPMC5313133 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature