Event-related potential and time-frequency endophenotypes for schizophrenia and psychotic bipolar disorder.

ABSTRACT:

Background

The investigators compared event-related potential (ERP) amplitudes and event-related oscillations across a broad frequency range during an auditory oddball task using a comprehensive analysis approach to describe shared and unique neural auditory processing characteristics among healthy subjects (HP), schizophrenia probands (SZ) and their first-degree relatives, and bipolar disorder I with psychosis probands (BDP) and their first-degree relatives.

Methods

This Bipolar-Schizophrenia Network on Intermediate Phenotypes sample consisted of clinically stable SZ (n = 229) and BDP (n = 188), HP (n = 284), first-degree relatives of schizophrenia probands (n = 264), and first-degree relatives of bipolar disorder I with psychosis probands (n = 239). They were administered

SUBMITTER: Ethridge LE 

PROVIDER: S-EPMC5314434 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature