Risk factors for central nervous system tumors in children: New findings from a case-control study.

ABSTRACT:

Background

Central nervous system tumors (CNS) are the most frequent solid tumor in children. Causes of CNS tumors are mainly unknown and only 5% of the cases can be explained by genetic predisposition. We studied the effects of environmental exposure on the incidence of CNS tumors in children by subtype, according to exposure to industrial and/or urban environment, exposure to crops and according to socio-economic status of the child.

Methods

We carried out a population-based case-control study of CNS tumors in Spain, covering 714 incident cases collected from the Spanish Registry of Childhood Tumors (period 1996-2011) and 4284 controls, individually matched by year of birth, sex, and autonomous region of residence. We built a covariate to approximate the exposure to indust

SUBMITTER: Ramis R 

PROVIDER: S-EPMC5315394 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature