The antibiotic resistome of swine manure is significantly altered by association with the Musca domestica larvae gut microbiome.

ABSTRACT: The overuse of antibiotics as veterinary feed additives is potentially contributing to a significant reservoir of antibiotic resistance in agricultural farmlands via the application of antibiotic-contaminated manure. Vermicomposting of swine manure using housefly larvae is a promising biotechnology for waste reduction and control of antibiotic pollution. To determine how vermicomposting influences antibiotic resistance traits in swine manure, we explored the resistome and associated bacterial community dynamics during larvae gut transit over 6 days of treatment. In total, 94 out of 158 antibiotic resistance genes (ARGs) were significantly attenuated (by 85%), while 23 were significantly enriched (3.9-fold) following vermicomposting. The manure-borne bacterial community showed a decrease in

SUBMITTER: Wang H 

PROVIDER: S-EPMC5315468 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature