Abnormal connectivity in the sensorimotor network predicts attention deficits in traumatic brain injury.

ABSTRACT: The aim of this study was to explore modifications of functional connectivity in multiple resting-state networks (RSNs) after moderate to severe traumatic brain injury (TBI) and evaluate the relationship between functional connectivity patterns and cognitive abnormalities. Forty-three moderate/severe TBI patients and 34 healthy controls (HC) underwent resting-state fMRI. Group ICA was applied to identify RSNs. Between-subject analysis was performed using dual regression. Multiple linear regressions were used to investigate the relationship between abnormal connectivity strength and neuropsychological outcome. Forty (93%) TBI patients showed moderate disability, while 2 (5%) and 1 (2%) upper severe disability and low good recovery, respectively. TBI patients performed worse than HC on the d

SUBMITTER: Shumskaya E 

PROVIDER: S-EPMC5315712 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature