Liver transplant recipients and prioritization of anti-HCV therapy: an Italian cohort analysis.

ABSTRACT:

Background and aims

In patients with hepatitis C virus (HCV), recurrence of infection after liver transplant (LT) is universal and associated with worst survival. We present the results of an Italian cohort to compare the 3-year outcome of HCV-Ab-positive and HCV-Ab-negative LT recipients and to assess the potential interaction between HCV-Ab sero-status and other risk factors for LT failure.

Methods

The study is a multicentre cohort including a sample of liver transplant centres. Participant's information was collected at the local level. The best functional form of variables was decided according to the objective methods based on information theory. Association between transplant failure and potential risk factors was assessed in univariate and multivariate Poisson regress

SUBMITTER: Lanini S 

PROVIDER: S-EPMC5317090 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature