Chlamydia related bacteria (Chlamydiales) in early pregnancy: community-based cohort study.

ABSTRACT:

Objectives

Serological case-control studies suggest that certain chlamydia-related bacteria (Chlamydiales) which cause cows to abort may do the same in humans. Chlamydiales include Waddlia chondrophila, Chlamydia abortus and Chlamydia trachomatis. Data on prevalence of Chlamydiales in pregnancy are sparse. Using stored urine samples from a carefully characterised cohort of 847 newly pregnant women recruited from 37 general practices in London, UK, we aimed to investigate the prevalence and types of Chlamydiales infections. We also explored possible associations with miscarriage or spontaneous preterm birth.

Methods

Samples were tested using W. chondrophila and pan-Chlamydiales specific real-time PCRs targeting the 16S rRNA gene. Samples positive on either PCR were subjected

SUBMITTER: Reid F 

PROVIDER: S-EPMC5317141 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature