On the Long-term Stability of Clines in Some Metabolic Genes in Drosophila melanogaster.

ABSTRACT: Very little information exists for long-term changes in genetic variation in natural populations. Here we take the unique opportunity to compare a set of data for SNPs in 15 metabolic genes from eastern US collections of Drosophila melanogaster that span a large latitudinal range and represent two collections separated by 12 to 13 years. We also expand this to a 22-year interval for the Adh gene and approximately 30 years for the G6pd and Pgd genes. During these intervals, five genes showed a statistically significant change in average SNP allele frequency corrected for latitude. While much remains unchanged, we see five genes where latitudinal clines have been lost or gained and two where the slope significantly changes. The long-term frequency shift towards a southern favored Adh S allel

SUBMITTER: Cogni R 

PROVIDER: S-EPMC5318857 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature