Isoprenaline versus nitroglycerine in head-up tilt test.

ABSTRACT:

Background

HUTT test is used in evaluation of syncope. Isoprenaline and isosorbide dinitrate are used to increase the sensitivity of the test. These drugs act by different mechanisms. We aimed to compare the results of isoprenaline with isosorbide dinitrate.

Methods and results

We studied 198 subjects referred for HUTT to our institute; those above the age of 35 years were not included in our study, because isoprenaline was not used commonly above this age; thus, only 90 subjects were analyzed. We found that isosorbide dinitrate resulted in more HUTT-positive results than isoprenaline by absolute risk difference of 26%; relative risk for positive isoprenaline was 60%, confidence interval 0.38-0.93, and P value of 0.03. There was no difference in frequency of types of respons

SUBMITTER: Bilagi UR 

PROVIDER: S-EPMC5319004 | biostudies-literature | 2017 Jan - Feb

REPOSITORIES: biostudies-literature