Different characteristics of mesenchymal stem cells isolated from different layers of full term placenta.

ABSTRACT:

Background

The placenta is a very attractive source of mesenchymal stem cells (MSCs) for regenerative medicine due to readily availability, non-invasive acquisition, and avoidance of ethical issues. Isolating MSCs from parts of placenta tissue has obtained growing interest because they are assumed to exhibit different proliferation and differentiation potentials due to complex structures and functions of the placenta. The objective of this study was to isolate MSCs from different parts of the placenta and compare their characteristics.

Methods

Placenta was divided into amniotic epithelium (AE), amniotic membrane (AM), chorionic membrane (CM), chorionic villi (CV), chorionic trophoblast without villi (CT-V), decidua (DC), and whole placenta (Pla). Cells isolated from each lay

SUBMITTER: Choi YS 

PROVIDER: S-EPMC5321410 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature