Automated numerical simulation of biological pattern formation based on visual feedback simulation framework.

ABSTRACT: There are various fantastic biological phenomena in biological pattern formation. Mathematical modeling using reaction-diffusion partial differential equation systems is employed to study the mechanism of pattern formation. However, model parameter selection is both difficult and time consuming. In this paper, a visual feedback simulation framework is proposed to calculate the parameters of a mathematical model automatically based on the basic principle of feedback control. In the simulation framework, the simulation results are visualized, and the image features are extracted as the system feedback. Then, the unknown model parameters are obtained by comparing the image features of the simulation image and the target biological pattern. Considering two typical applications, the visual feed

SUBMITTER: Sun M 

PROVIDER: S-EPMC5321435 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature