Prognostic factors for cerebral palsy and motor impairment in children born very preterm or very low birthweight: a systematic review.

ABSTRACT:

Aim

There is a large literature reporting risk factor analyses for poor neurodevelopment in children born very preterm (VPT: ≤32wks) or very low birthweight (VLBW: ≤1250g), which to date has not been formally summarized. The aim of this paper was to identify prognostic factors for cerebral palsy (CP) and motor impairment in children born VPT/VLBW.

Method

A systematic review was conducted using Medline, Embase, and Pyscinfo databases to identify studies published between 1 January 1990 and 1 June 2014 reporting multivariable prediction models for poor neurodevelopment in VPT/VLBW children (registration number CRD42014006943). Twenty-eight studies for motor outcomes were identified.

Results

There was strong evidence that intraventricular haemorrhage and periventricular

SUBMITTER: Linsell L 

PROVIDER: S-EPMC5321605 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature