Mapping white-matter functional organization at rest and during naturalistic visual perception.

ABSTRACT: Despite the wide applications of functional magnetic resonance imaging (fMRI) to mapping brain activation and connectivity in cortical gray matter, it has rarely been utilized to study white-matter functions. In this study, we investigated the spatiotemporal characteristics of fMRI data within the white matter acquired from humans both in the resting state and while watching a naturalistic movie. By using independent component analysis and hierarchical clustering, resting-state fMRI data in the white matter were de-noised and decomposed into spatially independent components, which were further assembled into hierarchically organized axonal fiber bundles. Interestingly, such components were partly reorganized during natural vision. Relative to resting state, the visual task specifically ind

SUBMITTER: Marussich L 

PROVIDER: S-EPMC5321894 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature