Identification of immune protective genes of Eimeria maxima through cDNA expression library screening.

ABSTRACT:

Background

Eimeria maxima is one of the most prevalent Eimeria species causing avian coccidiosis, and results in huge economic loss to the global poultry industry. Current control strategies, such as anti-coccidial medication and live vaccines have been limited because of their drawbacks. The third generation anticoccidial vaccines including the recombinant vaccines as well as DNA vaccines have been suggested as a promising alternative strategy. To date, only a few protective antigens of E. maxima have been reported. Hence, there is an urgent need to identify novel protective antigens of E. maxima for the development of neotype anticoccidial vaccines.

Methods

With the aim of identifying novel protective genes of E. maxima, a cDNA expression library of E. maxima sporozoites w

SUBMITTER: Yang X 

PROVIDER: S-EPMC5322808 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature