Exploratory analysis of osteoarthritis progression among medication users: data from the Osteoarthritis Initiative.

ABSTRACT:

Background

We conducted an exploratory analysis of osteoarthritis progression among medication users in the Osteoarthritis Initiative to identify interventions or pathways that may be associated with disease modification and therefore of interest for future clinical trials.

Methods

We used participants from the Osteoarthritis Initiative with annual medication inventory data between the baseline and 36-month follow-up visit (n = 2938). Consistent medication users were defined for each medication classification as a participant reporting at all four annual visits that they were regularly using an oral prescription medication at the time of the visit. The exploratory analysis focused on medication classes with 40 or more users. The primary outcome measures were medial ti

SUBMITTER: Driban JB 

PROVIDER: S-EPMC5322858 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature