Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus disease.

ABSTRACT:

Background

The non-specific symptoms of Ebola Virus Disease (EVD) pose a major problem to triage and isolation efforts at Ebola Treatment Centres (ETCs). Under the current triage protocol, half the patients allocated to high-risk "probable" wards were EVD(-): a misclassification speculated to predispose nosocomial EVD infection. A better understanding of the statistical relevance of individual triage symptoms is essential in resource-poor settings where rapid, laboratory-confirmed diagnostics are often unavailable.

Methods/principal findings

This retrospective cohort study analyses the clinical characteristics of 566 patients admitted to the GOAL-Mathaska ETC in Sierra Leone. The diagnostic potential of each characteristic was assessed by multivariate analysis and incorporat

SUBMITTER: Hartley MA 

PROVIDER: S-EPMC5322888 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature